Studies on complement fixation: II. The effect of heat on complement-fixing antibodies

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Studies on Complement Fixation

It is shown by complement fixation studies with protein antigens and specific immune rabbit sera that the rate of fixation of complement is determined by the concentration of antibodies in the immune sera, that the greater part of fixation of complement takes place during the 1st hour, and that fixation is practically completed at the end of 4 hours at ice box temperature. It is further shown t...

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The prolonged extraction of the tubercle bacillus with boiling ethyl alcohol, followed by one or more reprecipitations by chilling the hot alcoholic solution, easily yields a preparation very active as antigen in the complement fixation reaction. This preparation gives a precipitation reaction with high dilution of the normal blood serum of a number of species. The precipitation reaction presen...

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the washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests

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ژورنال

عنوان ژورنال: Journal of Infectious Diseases

سال: 1921

ISSN: 0022-1899,1537-6613

DOI: 10.1093/infdis/29.5.639